Combinatorial Chemistry & High Throughput Screening

Combinatorial Chemistry & High Throughput Screening (Comb Chem High T Scr, ISSN: 1386-2073) is a peer-reviewed scientific journal dedicated to advancing the fields of combinatorial chemistry, high-throughput screening, and related drug discovery technologies. Published by Bentham Science Publishers, the journal provides a platform for the dissemination of novel research and methodological innovations in the rapid identification and optimization of bioactive compounds. Its scope encompasses a wide range of topics, including library design and synthesis, assay development, automation, cheminformatics, and the application of high-throughput techniques in medicinal chemistry, pharmacology, and biotechnology. The journal publishes original research articles, comprehensive reviews, short communications, and thematic issues that highlight emerging trends and technologies. Its target audience includes academic researchers, pharmaceutical scientists, medicinal chemists, pharmacologists, and industry professionals involved in early-stage drug discovery and lead optimization. Notably, the journal offers both subscription-based and open access publishing options, allowing authors to choose the dissemination model that best suits their needs. With an Impact Factor of 1.7000 as of 2026, Combinatorial Chemistry & High Throughput Screening is currently positioned in the Q4 quartile within its subject area (classified as 4区医学 in the Chinese Academy of Sciences journal ranking system). While its impact factor places it in a lower tier, the journal remains a relevant resource for specialized, method-focused work in combinatorial and screening sciences, particularly for researchers seeking a venue for niche applications and incremental technological advances in the field.