Nature Biotechnology

Nature Biotechnology is a premier peer-reviewed journal published by Springer Nature, dedicated to the publication of original research and reviews that drive innovation at the interface of biology, engineering, and medicine. Its scope encompasses the development and application of novel technologies across the life sciences, with a strong emphasis on translational potential and real-world impact. Core topics include genomic and post-genomic technologies, gene editing and therapy, synthetic biology, computational and systems biology, protein engineering, nanobiotechnology, regenerative medicine, and biopharmaceutical discovery and manufacturing. The journal publishes a range of article types, including original research articles, brief communications, reviews, perspectives, and news features, as well as technical reports and correspondence. Its primary target audience comprises academic researchers, industry scientists, biotech entrepreneurs, and policy makers who seek cutting-edge advances that bridge fundamental discovery and commercial application. A notable feature is its commitment to open access options, allowing authors to make their work freely available under a Creative Commons license, while also offering a traditional subscription model. With an exceptional 2026 Impact Factor of 68.700, Nature Biotechnology is ranked in the Q1 quartile and is widely recognized as one of the most influential and prestigious journals in the field of biotechnology. Its standing as a top-tier publication reflects its rigorous peer-review process and its consistent role in shaping the direction of modern biological research and its industrial translation.